Use of Integrated Pulmonary Index to Predict Post-Operative Respiratory Adverse Events in High Risk Patients

Use of Integrated Pulmonary Index to Predict Post-Operative Respiratory Adverse Events in High Risk Patients - IPI-RAEs trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs062180014

Enrollment

200

Registered

2019-01-04

Start date

2019-03-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High risk patients undergoing general anesthesia

Interventions

The care team and patient will be blinded to the Capnostream 20p monitor's data for the patient's entire PACU/ICU stay or 2 hours, whichever is shorter.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients 18 years or older undergoing general anesthesia for one of following: -craniotomy -open upper abdominal surgery (including bariatric) -vascular surgery (including open aortic surgery and lower extremity bypass surgery) -surgical repair of hip fracture if patient has any of the following: albumin 30 mg/dL, dependent functional status, COPD, age >75 -Posterior fusion (Lumbar or Thoracic)

Exclusion criteria

Exclusion criteria: -Pregnant -Less than 18 years of age -Mechanically ventilated prior to surgery

Design outcomes

Primary

Measure	Time frame
Respiratory events/interventions logged: -Increase in oxygen delivery method (such as nasal cannula to high flow nasal cannula or non-rebreather, etc.) -Respiratory treatment (including albuterol, atrovent or racemic epinephrine) -Initiation of BiPap or intubation/mechanical ventilation -Administration of naloxone or flumazenil -Desaturation - defined as pulse oximetry below 90% sustained for greater than 2 minutes -Hypercarbia - defined as PaCO2 (from ABG) >50mmHg -Respiratory rate <8 breaths per minute -Administration of any dose of atropine or epinephrine -Other (specify)	—

Measure

Time frame

Respiratory events/interventions logged: -Increase in oxygen delivery method (such as nasal cannula to high flow nasal cannula or non-rebreather, etc.) -Respiratory treatment (including albuterol, atrovent or racemic epinephrine) -Initiation of BiPap or intubation/mechanical ventilation -Administration of naloxone or flumazenil -Desaturation - defined as pulse oximetry below 90% sustained for greater than 2 minutes -Hypercarbia - defined as PaCO2 (from ABG) >50mmHg -Respiratory rate <8 breaths per minute -Administration of any dose of atropine or epinephrine -Other (specify)

—

Countries

Japan, United States

Contacts

Public ContactSatoshi Suzuki

Okayama University Hospital

suzuki-s@mtc.biglobe.ne.jp+81-86-235-7778

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026