Volume Elastic Modulus as an Atherosclerotic Marker (Volume Elastic Modulus)

Volume Elastic Modulus Measured by Health Chronos TM2772 as a Marker of Atherosclerosis (Volume Elastic Modulus and Atherosclerosis) - Volume Elastic Modulus Measured by Health Chronos TM2772 as a Marker of Atherosclerosis (Volume Elastic Modulus and Atherosclerosis)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs062180013

Enrollment

Registered

2018-12-28

Start date

2018-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular risk factors (hypertension, dyslipidemia, or diabetes mellitus) or cardiovascular dis Atherosclerosis

Interventions

Measurements of TM-2772, FMD, and NID

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with hypertension, dyslipidemia, diabetes mellitus, smoking, or cardiovascular disease 2. Patients with age of 20 years old or more

Exclusion criteria

Exclusion criteria: 1. Unhealed wound in upper arm, stasis dermatitis, or shunt 2. Hypotension, cardiogenic shock 3. Angle-closure glaucoma 4. Head injury, intracranial hemorrhage 5. Severe anemia 6. Hypersensitivity to nitrate 7. Receiving treatment with phosphodiesterase 5 inhibitors or guanylate cyclase activators 8. Pregnant female 9. Judgement of an attending physician that an individual is ineligible for inclusion in the study

Design outcomes

Primary

Measure	Time frame
Associations of Volume Elastic Modulus measured by Health Chronos TM2772 with flow-mediated vasodilation (FMD), and nitroglycerine-induced vasodilation (NID)	—

Secondary

Measure	Time frame
1. Associations of Volume Elastic Modulus measured by Health Chronos TM2772 with cardiovascular risk parameters and ankle-brachial index 2. Associations between brachial artery cross-sectional area measured by Health Chronos TM2772 and brachial artery cross-sectional area measured by ultrasound 3. Safety evaluation	—

Contacts

Public ContactTatsuya Maruhashi

Research Institute for Radiation Biology and Medicine, Hiroshima University

55maruchin@gmail.com+81-82-257-5831

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026