cerebrospinal fluid hypovolemia cerebrospinal fluid hypovolemia
Conditions
Interventions
[Evaluation Tools]
The following assessment tools will be used:
Pain assessment: Visual Analogue Scale (VAS) (hereafter referred to as "VAS assessment")
Balance assessment: Berg Balance Scale (BBS) (
Lumbar puncture
Sponsors
Eiichi Nakai
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants who meet at least one of the following conditions will be included: 1. Patients with apparent orthostatic headache and/or neck pain that improves within 5 minutes after assuming the supine position. 2. Patients who have persistent orthostatic symptoms such as lightheadedness or dizziness.
Exclusion criteria
Exclusion criteria: Participants who meet any of the following conditions will be excluded: 1. Patients with a bleeding tendency. 2. Patients in whom lumbar puncture is difficult or contraindicated. 3. Pregnant women. 4. Patients deemed ineligible by the investigator. 5. Patients younger than 18 years of age at the time of consent (regardless of sex).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We will compare changes in orthostatic subjective symptom scores before and after intrathecal administration of ARTCELEB cerebrospinal surgery irrigation solution. In addition, we will examine the association between these symptom score changes and cerebrospinal fluid pressure. | — |
Secondary
| Measure | Time frame |
|---|---|
| The safety of the CSF refill test will be evaluated by assessing adverse events before and after administration of ARTCELEB cerebrospinal surgery irrigation solution. | — |
Contacts
Public ContactNakai Eiichi
Kochi Medical School Hospital
Outcome results
None listed