Adolescent Idiopathic Scoliosis
Conditions
Interventions
During posterior correction and fusion surgery for scoliosis, vancomycin hydrochloride powder for intravenous injection is applied directly into the surgical wound. The dosage is 1g.
Sponsors
Shinohara Kensuke
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.From 6 to 23 years old at the time of obtaining consent 2.body weight is 25 kg or more 3.Diagnosed with scoliosis who undergo posterior corrective fixation 4.Individuals who, after receiving a thorough explanation of this study and fully understanding its purpose, have provided written consent freely and voluntarily, either by themselves or through a legally authorized representative
Exclusion criteria
Exclusion criteria: 1.A known allergy to vancomycin 2.A preoperative serum creatinine (Cr) level of 1.2 mg/dL or higher 3.A history of vancomycin administration within 30 days from the date of surgery. 4.Deemed unsuitable as research subjects by the principal investigator or sub-investigators for any other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Renal Dysfunction | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Abnormally high postoperative vancomycin blood concentration 2.Adverse events other than renal dysfunction 3.Incidence of surgical site infection | — |
Contacts
Public ContactKazutaka Yamashita
Okayama University Hospital
Outcome results
None listed