cerebrospinal fluid hypovolemia cerebrospinal fluid hypovolemia
Conditions
Interventions
Perform lumbar puncture using the same technique as CT myelography, and inject 10 mL of Isovist 240 intrathecally. After intrathecal administration of Isovist 240, the patient should remain in bed res
Lumbar puncture
Sponsors
Eiichi Nakai
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients whose cerebrospinal fluid pressure has been confirmed to be less than 10 cmH2O at least once in the past and who are strongly suspected of having cerebrospinal fluid depletion. (2) Patients in whom leakage sites cannot be identified by CT myelography (3) Age 18 and above at the time of consent acquisition (gender unspecified)
Exclusion criteria
Exclusion criteria: (1) Patients with suspected symptoms of contrast agent allergy in the past (2) Patients with other acute illnesses (3) Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of identified leakage sites of cerebrospinal fluid using boosted CT Myelography. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Complications such as bleeding and neurological disorders associated with the implementation of boosted CT myelography. (2) Side effects such as headache, dizziness, nausea, and fever associated with intrathecal injection of ARTCEREB. (3) Overall mortality. (4) Other adverse events. | — |
Contacts
Public ContactNakai Eiichi
Kochi University Medical hospital
Outcome results
None listed