Scheduled non-cardiac surgeries under general anesthesia
Conditions
Interventions
69 patients are divided randomly into three groups: bolus group A, bolus group B and continuous group, and 23 patients are involved in each group. In advance, anesthesiologists or nurses secure an int
D018686
general anesthesia, remimazolam
Sponsors
Miyoshi Hirotsugu
Kido Kenshiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients undergoing scheduled non-cardiac surgeries under general anesthesia 2. Patients aged 18 to 80 3. Patients with ASA-PS classification 1 or 2 4. Patients with BMI 18.5 to 30 5. Patients who can understand our explanation well enough, agree and sign the consent forms of their own will
Exclusion criteria
Exclusion criteria: 1. Patients with heavy use of alcohol (over 60 g per day) 2. Patients who have or previously had an addiction to alcohol or any other drugs 3. Patients with common use of benzodiazepines 4. Patients with acute angle-closed glaucoma, myasthenia gravis or hypersensitivity to remimazolam 5. Patients with severe mental disorders 6. Patients with encephalopathy 7. Patients who are pregnant or lactating 8. Researchers who are directly involved in this study or other clinical studies, or their families 9. Patients who are judged inappropriate for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time from administration of general anesthetics to loss of consciousness (seconds) | — |
Secondary
| Measure | Time frame |
|---|---|
| The rate of change in blood pressure and heart rate during induction of general anesthesia | — |
Contacts
Public ContactKenshiro Kido
Hiroshima University Hospital
Outcome results
None listed