Esophageal motility disorders
Conditions
Interventions
Treatment is given during an Per-oral endoscopic myotomy using two submucosal injection materials (Sodium hyaluronate solution, sodium alginate solution, physiological saline, etc.) supplemented with
Sponsors
Ikeda Yoshio
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Cases diagnosed with esophageal motility disorders (esophageal achalasia and related disorders) by high resolution manometry (HRM), esophagography, upper gastrointestinal endoscopy, etc., for which POEM is indicated. It does not matter whether previous treatment was given or not.
Exclusion criteria
Exclusion criteria: 1)Patients with a history of hypersensitivity to carbazochrome sodium sulfonate 2)Cases of hereditary fructose intolerance 3)Cases in which general anesthesia is difficult to perform 4)Cases with infections requiring systemic treatment 5)Pregnancy, possible pregnancy, or breastfeeding 6)Patients with psychosis, psychiatric symptoms, or dementia for whom participation in the study is judged to be difficult 7)Patients with respiratory diseases requiring continuous oxygen administration 8)Patients with uncontrolled hypertension 9) Patients with uncontrolled diabetes mellitus 10) Other cases judged inappropriate by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of proper submucosal tunneling in POEM | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) LCI (Linked-Color Imaging) color recognition improvement 2) Incidence of perioperative adverse events 3) Treatment time 4) Symptom improve rate (Eckardt score) 5) Incidence of gastroesophageal reflux after POEM | — |
Contacts
Public ContactHideomi Tomida
Ehime University Hospial
Outcome results
None listed