cerebrospinal fluid hypovolemia cerebrospinal fluid hypovolemia
Conditions
Interventions
In the CSF refill test, we evaluate the pain by standing and measure the time of walking 10m before the CSF refill test. Then, lumbar puncture is performed by a general lumbar puncture method to confi
Lumbar puncture
Sponsors
Nakai Eiichi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet all of the following criteria are targeted. 1. Patients with overt orthostatic headache and suspected cerebrospinal fluid hypovolemia 2. Patients with CSF pressure of 100mmH2O or less 3. Patients over 18 years old 4. Patients who have given written consent to participate in this study(If you are a minor or you do not have the ability to consent, you will be a substitute)
Exclusion criteria
Exclusion criteria: Patients who fall under any of the following are excluded. 1. Patients who tend to bleed 2. Patients who have difficulty with lumbar puncture 3. Pregnant woman 4. Patients recognized by doctors ineligible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We examine the safety of the CSF refill test by assessing adverse events before and after injecting 20 mL of ARTCEREB. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. We measure the initial, intermediate and final pressures of cerebrospinal fluid during lumbar puncture. 2. We evaluate the VAS score before and after ARTCEREB intrathecal injection. 3. We measure the time to walk 10 m before and after intrathecal injection. | — |
Contacts
Public ContactEiichi Nakai
Kochi Medical School Hospital
Outcome results
None listed