unruptured intracranial aneurysm
Conditions
Interventions
Adenosine-induced hypotension during aneurysmal clipping
Monitoring using electrocardiogram, arterial blood pressure, central venous presssure
Standby transcutaneous pacing in preparation to temporary
Sponsors
HISHIKAWA Tomohito
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 20 years or older 2. Patients with written informed consent 3. Patients who are planned to receive clipping surgery for unruptured intracranial saccular aneurysm in our institute 4. Cases in which surgeon judged the decompression of aneurysm as effective in clipping
Exclusion criteria
Exclusion criteria: 1. coronary artery stenosis 2. Past history of ischemic heart disease 3. Aortic valve stenosis 4. Obstructive hypertrophic cardiomyopathy 5. Paroxysmal atrial fibrillation 6. Atrioventricular block 7. Bronchial asthma 8. Chronic obstructive pulmonary disease 9. 80 years or older 10. Pregnant woman, nursing woman 11. Patients who simultaneously receive clipping surgery for multiple aneurysms in one operation 12. Patients who were judged as no interest or having possibility of interruption of assessment of reserach by research responsible physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified Rankin Scale (mRS) at 30 days after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Completeness of clipping 2. Total doses of adenosine 3. Duration between adenosine administration and clipping 4. mRS at discharge and at 90 days after surgery 5. Prevalence and duration of hypotension by adenosine administration 6. Adverse events caused by adenosine administration 7. Other adverse events | — |
Contacts
Public ContactTomohito HISHIKAWA
Okayama University Hospital
Outcome results
None listed