Tear meniscus height after stimulated Menthol and comparison of lacrimation ability with Schirmer's test

Measurement of Tear meniscus height after stimulated l-Menthol using Anterior segment optical coherence tomography and comparison of lacrimation ability with Schirmer's test

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs061190033

Enrollment

Registered

2020-02-12

Start date

2020-07-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

L-menthol was instilled, and the tear meniscus height before, after 1, 2, 3, 4, 5 minutes after the instillation was measured by AS-OCT, and compare with Schirmer's test.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Normal Volunteers 30 people, Dry eye patients 30 people criteria: 1. Over 20 years old, 2. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Not written informed consent, 2. Inflammatory eye disease, 3. Using Punctal plug as a treatment for Dry eye or Dacryo Lacrimal Disease

Design outcomes

Primary

Measure	Time frame
Stimulation of tear fluid height measurement after instillation of l-menthol by AS-OCT Utility as a lacrim secretory function test	—

Secondary

Measure	Time frame
Correlation between tear meniscus height measurement and Schirmer's test after l-menthol instillation by AS-OCT	—

Contacts

Public ContactYuki Takezawa

Ehime University Hospital

yuki-tak@m.ehime-u.ac.jp+81-89-960-5361

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026