Head and neck squamous cell carcinoma
Conditions
Interventions
Treatment of dietary glucosylceramide
glucosylceramide
Sponsors
Fujiwara Kazunori
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histological type is squamous cell carcinoma 2)Primary site is paranasal sinus, oral cavity, oropharynx, hypopharynx, larynx. 3)Stage3 or stage4A,4B, which had surgery, radiation and chemoradiation. 4)Cases identified as complete response by histological examination and imaging test. 5)20 years of age and older. 6)Ability of oral intake 7)Performance status (PS) 0-1 8)No abnormalities of Bone marrow function, renal function, and liver function within the first 14 days. 9)Informed concent is obtained.
Exclusion criteria
Exclusion criteria: 1)Cases with allergic symptom by konnyaku. 2)Cases with infection disease requiring treatment 3)Cases with gastrointestinal disease requiring treatment 4)Cased with interstitial pneumonia and lung fibrosis. 5)Cases with poorly controlled diabetes. 6)Cases with severe liver damage. 7)Cases with severe diarrhea. 8)Pregnant woman or potential. 9)Cases deemed inappropriate by principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease free survival (DFS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Relapse-free survival (RFS) Overall survival Adverse event Side reaction | — |
Contacts
Public ContactKazunori Fujiwara
Tottori University Hospital
Outcome results
None listed