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COPD simultaneously measurement of Sweat lactate study

COPD simultaneously measurement of Sweat lactate study - COSMOS-L study

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs052240205
Enrollment
45
Registered
2024-12-06
Start date
2024-12-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease(COPD) COPD

Interventions

Anaerobic metabolic thresholds are measured by wearing a sweat measurement device (sweat lactate sensor) during cardiopulmonary exercise testing in COPD patients.

Sponsors

ASAI KAZUHISA
Lead Sponsor
Grace imaging, Inc.
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients with stable COPD without prior exacerbation for 4 weeks (regardless of severity) (2) Age 40 years or older (at the time of consent). (3) Patient is an outpatient.

Exclusion criteria

Exclusion criteria: (1) Patients with the following contraindications to cardiopulmonary exercise testing Acute myocardial infarction (onset 3-5 days) Unstable angina pectoris Treatment-resistant arrhythmia Syncope Active endocarditis Acute myocarditis and pericarditis Symptomatic aortic stenosis Acute pulmonary embolism or infarction Lower limb venous thrombosis Suspected dissected aorta Treatment-resistant bronchial asthma Pulmonary oedema SpO2 200 mmHg systolic, >120 mmHg diastolic) Tachyarrhythmia or bradyarrhythmia Severe atrioventricular block Hypertrophic cardiomyopathy Severe pulmonary hypertension Pregnancies in the third trimester or pregnancies with complications Electrolyte abnormalities Orthopaedic disease with restricted exercise (2) COPD patients with an exacerbation within the 4 weeks preceding the time of obtaining consent. (3) Patients with psychosis or psychiatric symptoms that make it difficult for them to participate in research. (4) Other patients deemed inappropriate by the principal investigator

Design outcomes

Primary

MeasureTime frame
Correlation between anaerobic metabolic thresholds in COPD patients using sweat measurement devices and anaerobic metabolic thresholds using the exhaled gas analyser V-slope method

Secondary

MeasureTime frame
Correlation between respiratory function and age with anaerobic metabolic threshold (ratio of anaerobic metabolic threshold by breath gas analysis and anaerobic metabolic threshold by sweat lactate sensor) Correlation between anaerobic threshold, VO2max and physical activity

Contacts

Public ContactKAZUHISA ASAI

Osaka Metropolitan University Hospital

kazuasai@omu.ac.jp+81-6-6645-3916

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026