Patients with ASA physical status of 1 and 2, scheduled for surgery under total intravenous anesthes
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients over 20 years old at the time of informed consent 2. Patients with ASA physical status of 1 and 2 who are scheduled for surgery under general anesthesia 3. Patients who understand the contents of this study and are willing to provide written informed consent for participation in this study
Exclusion criteria
Exclusion criteria: 1. Patients with a history of hypersensitive to propofol, remifentanil, rocuronium or sugammadex 2. Patients who cannot connected BIS Sensor for placement on the forehead 3. Patients who cannot received rocuronium after first single dose 4. Patients who cannot measured non-invasive sphygmomanometer 5. Patients undergoing surgery with hypothermia 6. Patients undergoing cardiovascular surgery 7. Patients with supraventricular rhythm irregularities such as atrial fibrillation, atrial flutter, or sinus arrhythmia 8. Patients with expected blood loss of 1000 mL or more 9. Pregnant patients or patients having a possibility of pregnancy. Patients who are breast feeding or attempting to become pregnant 10. Pregnant patients or patients having a possibility of pregnancy. Patients who are breast feeding or attempting to become pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of time the mean blood pressure was maintained at 65 mmHg or higher during the evaluation period | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Percentage of time during the evaluation period when esSVI was below threshold 2. Total and hourly doses of infusion fluids used during the evaluation period 3. Total dose of phenylephrine used during the evaluation period 4. Number of single doses of phenylephrine used during the evaluation period 5. Urine and bleeding volume 6. Water balance 7. Ea Value | — |
Contacts
University of Fukui Hospital