Examination of the effect of nasal irrigation in patients with cedar pollinosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs052220146

Enrollment

Registered

2023-01-05

Start date

2023-02-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cedar pollinosis cedar, pollinosis

Interventions

Groups A and B only Rinse the left and right nasal passages twice a day with 50 mL of normal saline or a special cleaning solution

Nasal irrigarion, saline solution

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Faculty members working at the University of Fukui Matsuoka Campus or students enrolled in the University of Fukui Faculty of Medicine 2)A person who can obtain written consent from the person 3)Those who have a positive antigen-specific IgE antibody test at the time of pre-registration test with cedar pollen 4)Those who develop allergic symptoms every year during the cedar pollen allergy season. 5)Those who comply with the compliance rules while participating in this research, undergo medical examinations and examinations specified in this research plan, and are able to report symptoms, etc.

Exclusion criteria

Exclusion criteria: 1)People with a nasal irrigation rate of 80% or less 2)In the case of using therapeutic drugs for cedar pollinosis, those who started use, discontinued use, or changed the dosage during the period from 3 days prior to the start of the study to the end of the study. 3) Those who did not take the two tests after registration within the period 4)Persons who are judged by the investigator to be inappropriate for enrollment in this research

Design outcomes

Primary

Measure	Time frame
JRQLQ (Nasal symptom questionnaire)	—

Secondary

Measure	Time frame
1)Blood allergy test (total IgE level, antigen-specific IgE level) 2)Background of Research Participants 3)Nasal findings: edema of the nasal mucosa, color of the nasal mucosa, the degree of dryness of the nasal mucosa 4)Intranasal flora 5) Nasal discharge collection: determination of cedar-specific IgE antibodies, albumin, and short-chain fatty acids in nasal secretions, Proteins, peptide mixtures, metabolites of glycolytic systems, amino acids, organic acids, etc. 6)Nasal NO value 7)Comprehensive analysis of genes in nasal mucosal epithelial cells	—

Measure

Time frame

1)Blood allergy test (total IgE level, antigen-specific IgE level) 2)Background of Research Participants 3)Nasal findings: edema of the nasal mucosa, color of the nasal mucosa, the degree of dryness of the nasal mucosa 4)Intranasal flora 5) Nasal discharge collection: determination of cedar-specific IgE antibodies, albumin, and short-chain fatty acids in nasal secretions, Proteins, peptide mixtures, metabolites of glycolytic systems, amino acids, organic acids, etc. 6)Nasal NO value 7)Comprehensive analysis of genes in nasal mucosal epithelial cells

—

Contacts

Public ContactTakabayashi Tetsuji

University of Fukui Hospital

tetsuji@u-fukui.ac.jp+81-776-61-8407

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026