Liver disease, or a healthy donor for living-donor liver transplantation.
Conditions
Interventions
After obtaining written consent, eligible participants are registered. Using EDC system, participants are randomly assigned to "waterjet device group" or "ultrasonic device group". Liver resection is
Sponsors
Kawai Manabu
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age 20 years or older. (2) ECOG Performance Status 0 to 2. (3) Written consent provided. (4) Scheduled to undergo (open/laparoscopic) liver resection due to liver disease, or to undergo liver resection as a donor for living-donor liver transplantation. (5) Scheduled to undergo the following surgical procedures: right lobectomy, left lobectomy, right posterior sectionectomy, segment VII segmentectomy (for patients with liver disease) and right lobectomy, left lobectomy (for donors)
Exclusion criteria
Exclusion criteria: (1) Venous tumor thrombus (Vv2, 3). (2) Biliary tumor thrombus (B3, 4). (3) Needing biliary or vascular reconstruction. (4) Dissection area overlaps with area of previous partial hepatectomy. (5) Difficulty in taping hepatoduodenal ligament. (6) Requiring resection of other organs except for gallbladder. (7) BMI of 30 or more. (8) Child-Pugh grade B or C. (9) Platelet count 1.5 mg/dL). (13) Severe respiratory dysfunction (forced expiratory volume in 1 second <1L or requiring rest because of shortness of breath during 100m or several minutes' walking). (14) Other non-appropriate conditions, as determined by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood loss during liver resection | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Total blood loss amount during surgery. (2) Blood loss amount per resected area during liver parenchymal resection. (3) Total operating time. (4) Operating time during liver parenchymal resection. (5) Transection speed. (6) Incidence of blood transfusion. (7) Incidence of postoperative complications. (8) Perioperative mortality. (9) Postoperative days in hospital. | — |
Contacts
Public ContactMasaki Ueno
Wakayama Medical University Hospital
Outcome results
None listed