Prostate cancer
Conditions
Interventions
Use the analgesic protocol with a device not approved in Japan (PMD-200)
Sponsors
Tanaka Nobuhiro
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Male patients undergoing scheduled robot-assisted laparoscopic radical prostatectomy 2) Patients who were classed as American societyof anesthesiologists performance status (ASA-PS) 1-3 3) Patients aged between 20 and 85 years old 4) Patients who have given written consent to participate in the study
Exclusion criteria
Exclusion criteria: 1) Patients undergoing emergency surgery applied for the day 2) Patients taking beta-blockers, or applying patches for this drug 3) Patients taking oral steroids 4) Patients who cannot secure the measurement site due to a amputation of the finger or lesion on the nail 5) Patients with inability to give consent 6) Patients who have been judged inappropriate in the study by the investigator or sub-investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of intraoperative remifentanil usage (Total amount of remifentanil divided by the usagetime (min) and ideal body weight (kg) ) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Comparison of biomarker values (IL-6, CRP, cortisol) between the two groups 2) Changes in NoL values before and after events such as intubation, initiation of insufflation and re positioning in laparoscopic surgery 3) Numerical Rating Scale (NRS) values on the day of surgery (2 hours after surgery), 1, 2, 3, and 7 days after surgery, and 3 months after surgery 4) Perioperative opioid consumption 5) Presence of chronic postsurgical pain | — |
Contacts
Public ContactNobuhiro Tanaka
Nara Medical University Hospital
Outcome results
None listed