upper gastrointestinal epithelial tumor upper gastrointestine, epithelial tumor
Conditions
Interventions
Randomly assign patients to "Group A for WLI and LCI" or "Group B for LCI alone" for endoscopy.
endoscopy, randomize, LCI, WLI
Sponsors
Dohi Osamu
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet all of the following criteria willbe included 1) Patients with previous pharyngeal, esophageal, or gastric epithelial tumors (after endoscopic treatment, radiotherapy, or chemotherapy) or untreated lesions described above undergoing follow-up and scheduled for surveillance endoscopy. 2) Patients without upper gastrointestinal epithelial lesions (head and neck, esophagus, stomach) to be treated. 3) Patients must be at least 20 years old and less than 89 years old (as of the date of enrollment). 4) Written consent has been obtained from the patient prior to enrollment in the study.
Exclusion criteria
Exclusion criteria: Patients who fall into any of the following categories will not be included in this study. 1. Patients with a history of surgical resection of the upper gastrointestinal tract . 2. Patients who are in poor general condition and are expected to have difficulty in endoscopy after one year. 3. Patients with severe comorbidities with a predicted prognosis of less than one year. 4. Patients with any of the following complications 1. Severe infection or organ failure 2. Carcinoma undergoing chemotherapy or radiation therapy 3. Bleeding tendency due to thrombocytopenia or abnormal blood coagulation disease 5. Patients for whom biopsy is deemed impossible due to antithrombotic medication. 6. Pregnant or lactating women. 7. Patients who are judged by the principal investigator or sub-investigator to be inappropriate for participation in this study for other safety reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients with gastric epithelial tumors detected | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of holders of gastric epithelial tumorsdetected in prior WLI observation (Group A) and LCI observation (Group B) Percentage of patients with epithelial gastrictumor detected in group A and group B at the second endoscopy Percentage of patients with epithelial tumor detected of pharynx and esophagus in WLI observation (group A) and LCI observation (group B) Observation time (total observation timeexcluding treatment time by each mode, and observation time by site) Presence of serious adverse events Diagnostic accuracy of epithelial tumors (diagnostic accuracy of epithelial tumors relative to the number of biopsies by mode) Percentage of lesions of gastric epithelial tumors by years of experience (expert and non-expert) Percentage of lesions of gastric epithelial tumors by endoscope scope (fine diameter and other) Percentage of lesions of gastric epithelial tumors by light source (laser/LED) | — |
Contacts
Public ContactKazuyo Futahasi
University Hospital Kyoto Prefectural University of Medicine
Outcome results
None listed