Effect of CO2 therapy on post-polio syndrome

Exploratory study of efficacy and safety of transcutaneous CO2 application for post-polio syndrome. - Effect of CO2 therapy on post-polio syndrome

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs052180083

Enrollment

Registered

2019-02-28

Start date

2015-02-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-polio syndrome

Interventions

Transcutaneous application of CO2 for leg (20min 2 times/week)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1 Patients of post-polio syndrome with muscle weekness 2 Aged over 20 yrs 3 Patients who can consent in writting

Exclusion criteria

Exclusion criteria: 1 Ichemic limb (Fontaine 3-4) 2 Chronic heart failure (NYHA 4) 3 Precnancy (including possibility) 4 Respiratory failure (%VC<60%) 5. Sever anemia (Hb <7.0g/dl) 6. Large skin ulcer, skin trouble 7 Resercher's detamination of unsuitable of this study

Design outcomes

Primary

Measure	Time frame
Muscle power (12 week, Micro-FET, Knee extensor) Adverse events	—

Secondary

Measure	Time frame
Muscle power (12 week, Micro-FET, Knee extensor, Ankle extensor, flexor) Visual analog scale of pain, cold sense and general EMG (Quadriceps, Tibialis anterior, Traiceps surae) Thermography SPP	—

Countries

A, Japan, N

Contacts

Public ContactYoshitada Sakai

Kobe University Hospital

yossit@med.kobe-u.ac.jp+81-78-382-6826

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026