Pilot Study on the Effect of PicoPrep as a Bowel Preparation on Visualization Quality in Small Bowel Capsule Endoscopy.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs051250181

Enrollment

Registered

2026-01-07

Start date

2026-01-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients indicated for small bowel capsule endoscopy for diagnostic evaluation

Interventions

Patients receiving PicoPrep as a bowel preparation regimen before undergoing capsule endoscopy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing small bowel capsule endoscopy 2. Aged 18 years or older at the time of obtaining informed consent 3. Able to take oral laxatives 4. Patients who have provided written informed consent of their own free will to participate in this clinical study

Exclusion criteria

Exclusion criteria: 1. Patients with severe renal impairment (eGFR < 30 mL/min/1.73 m2). 2. Patients with severe heart failure (NYHA Class III or IV). 3. Patients with hyponatremia (serum sodium < 136 mEq/L) or hypokalemia (serum potassium < 3.5 mEq/L). 4. Patients with a history of surgical resection of the gastrointestinal tract (excluding appendectomy). 5. Patients who show evidence of impaired gastrointestinal passage on transit studies, or who are suspected of having intestinal obstruction or perforation. 6. Patients with toxic megacolon. 7. Patients suspected of having an acute abdomen. 8. Patients with a history of hypersensitivity to any component of PicoPrep. 9. Patients receiving iron supplementation who, for clinical reasons, are unable to comply with the discontinuation required in this study (cessation at least 7 days before examination). 10. Any other patients deemed inappropriate for inclusion in this clinical study by the investigator.

Design outcomes

Primary

Measure	Time frame
Image Quality Score of the Small Bowel Mucosa	—

Secondary

Measure	Time frame
Detection of pathological findings (bleeding, ulcerations, or vascular abnormalities) Evaluation of adequacy of bowel cleansing(whether an image quality score of 2.25 or higher was achieved) Completion of small bowel capsule endoscopy to the cecum within the recording time Measurement of small bowel transit time	—

Contacts

Public ContactNorihiro Okamoto

Kobe University Hospital

nokmt@med.kobe-u.ac.jp+81-78-382-6305

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026