allergic rhinitis caused by mite allergic rhinitis caused by mite, nasal provocation test
Conditions
Interventions
Nasal provocation by mite allergen
Nasal provocation, mite allergen
Sponsors
Imoto Yoshimasa
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with symptoms of allergic rhinitis (sneezing, watery nose, nasal congestion) . 2. Irrespective of gender 3. Patients aged 20 to 65 years at the time of consent 4. Patients who understand the contents of this study and are willing to provide written informed consent for participation in this study
Exclusion criteria
Exclusion criteria: 1. Patients with current and/or past history of bronchial asthma. 2. Patients who have previously received immunotherapy for mite allergic rhinitis. 3. Patients receiving antiallergic drugs. 4. Pregnant women and patients who may be pregnant. 5. Patients on nonselective beta-blockers. 6. Patients taking tricyclic antidepressants and monoamine oxidase inhibitors (MAOIs). 7. Patients with severe cardiac and pulmonary diseases and hypertension. 8. Patients with malignant tumors, or systemic malignancies affecting the immune system, or systemic diseases affecting the immune system 9. Patients who participated in another clinical study within 4 months. 10. Patients who are unable to take biologics withdrawal during the study period from 12 weeks prior to nasal provocation test. 11. Patients who are unable to take oral steroids withdrawal during the study period from 12 weeks prior to nasal provocation test. 12. Other patients regarded as inappropriate by the principal investigator and/or sub-investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Percentage of positive evoked reactions based on nasal symptoms and findings 2.Safety up to 24 hours after nasal provocation test | — |
Secondary
| Measure | Time frame |
|---|---|
| Compartment with mite allergen skin reaction | — |
Contacts
Public ContactYoshimasa Imoto
University of Fukui Hospital
Outcome results
None listed