Clinical Effects of Highly Absorptive Curcumin (curcurouge) on knee osteoarthritis

Clinical Effects of Highly Absorptive Curcumin (curcurouge) on knee osteoarthritis -compared with hialuronic acid knee injections-

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs051230130

Enrollment

100

Registered

2023-11-17

Start date

2023-11-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis knee joint medial type

Interventions

Highly Absorptive Curcumin (curcurouge) on knee o steoarthritis for three months

D046650

curcumin, oral intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Medial knee osteoarthritis and KL classification I or II or III, 2) over 40 years. 3) VAS before starting is more than 30/100, 4) consent of patient , 5) outpatient

Exclusion criteria

Exclusion criteria: 1)the patients who take more than 2 kinds of anti-coagulant drugs 2)Severe renal dysfunction or dialysis 3)severe liver dysfunction or liver cirrhosis 4)severe cardiovas cular diseases 5)severe cerebrovascular dysfuncti on 6)severe diabetes mellitus 7)curcumin abuse patients 8)previous knee surgery or intraarticular i njection for experimental period or steroid intraart icular injection before 2 months or steroid oral int ake before 4 weeks 9)patient who must be exclud ed by the scientific responsible doctor

Design outcomes

Primary

Measure	Time frame
JKOM, VAS, JOA knee OA score, KOOS Japanese version,dependence of N SAIDs	—

Secondary

Measure	Time frame
Time up and go, knee range of motion biochemic al analysis of blood, responder rate of OMERACT-OARSI	—

Contacts

Public ContactYasuaki Nakagawa

Japan Baptist Medical Foundation

yasu0202nakagawa@gmail.com+81-75-781-5191

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026