Esophageal cancer minimally invasive esophagectomy, enteral feeding
Conditions
Interventions
In this study, enteral nutrition intervention will be performed in patients who have undergone minimally invasive esophagectomy, and enteral feeding tube placement.
minimally invasive esophagectomy, enteral feeding
Sponsors
Goto Hironobu
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age 18 years or older at the time of consent (2) Diagnosed as cStage I/II/III (12th edition of the Esophageal Cancer Treatment Protocol) and underwent subtotal esophagectomy, primary reconstruction, enteral tube placement (3) ECOG-PS 0-2 (4) Able to take oral intake before surgery (5) Expected to undergo surgery within 60 days of study enrollment (within 60 days of completion of chemotherapy for patients undergoing preoperative chemotherapy) (6) Patients are expected to be able to take oral intake for 3 months after surgery (7) The patient's free written consent to participate in the study has been obtained.
Exclusion criteria
Exclusion criteria: (1) The subject is allergic to oral nutritional supplements. (2)Identified as allergic to any of the ingredients (especially soy and gelatin) in the test nutritional product, Hinex E-Gel LC. (3) The subject has difficulty obtaining consent due to dementia or mental illness requiring treatment. (4) The patient is taking steroids or immunosuppressive drugs due to an autoimmune disease, etc. (5) Complicated viral infection requiring treatment. (6) Other conditions deemed inappropriate by the Principal Investigator or Principal Investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate adherence to dosing at 2 months after esophagectomy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of Hinex-Egel administration ECOG-PS (2 months, 3 months, 6 months after surgery) Nutritional index items by blood biochemical tests (preoperative, 2 months, 3 months, and 6 months postoperatively) Body weight loss rate at 2, 3, and 6 months after esophagectomy Fat mass and skeletal muscle mass using CT images (preoperatively and 6 months postoperatively) Occurrence of disease, etc. (gastrointestinal symptoms related to protocol treatment: diarrhea, constipation, vomiting, etc.) | — |
Contacts
Public ContactHironobu Goto
Kobe University Hospital
Outcome results
None listed