Acute myocardial inferction (ST-elevation myocardial infarction, non-ST-segment elevation myocard)
Conditions
Interventions
Bolus administration of sodium bicarbonate immediately before contrast medium administration
Sponsors
Watanabe Makoto
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 20 years old and over 2 Patients heading directly to the cardiac catheterization laboratory from the emergency outpatient department or patients with in-hospital onset 3 Patients with suspected acute myocardial infarction based on changes in electrocardiogram, elevation of myocardial enzyme, or echocardiography 4 Patients who consented to patient or legal acceptable representative in the study
Exclusion criteria
Exclusion criteria: 1 Patients with shock or cardiopulmonary arrest upon arrival at the emergency department 2 Patients with impaired consciousness, orthopnoea, or needing tracheal intubation and non-invasive positive pressure ventilation (NIPPV) upon arrival at emergency department 3 Patients who received oral or intravenous sodium bicarbonate before CAG was performed 4 Patients who are allergic to contrast agents at the time of registration 5 Patients who undergoing dialysis 6 Patients who uncontrolled hyperthyroidism or hypothyroidism 7 Patients who received contrast media within 7 days of CAG or PCI 8 Patients who did not undergo PCI as the result of CAG 9 Patients who did not diagnosed with acute myocardial infarction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CIN occur within 48 +- 12 hours CIN is defined by as follows: 1: SCr increased by more than 0.5 mg/dL from the time of enrollment 2: SCr increased by more than 25% from the time of enrollment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Acute renal dysfunction (SCr increase of >=1.5 times or >=0.3 mg/dL based on SCr at enrollment) occur within 48+-12 hours 2 CIN(SCr increased by 0.5 mg / dL or more or 25% or more based on SCr at enrollment) occur within 72 +- 12 hours 3 SCr increase after Catheterization / treatment at 24 +- 12 hours, at 48 +- 12 hours, at 72 +- 12 hours | — |
Contacts
Public ContactMakoto Watanabe
Nara Medical University Hospital
Outcome results
None listed