Preventive effect of amino acids on CSA-AKI

Effect of Amino acids for preventing Cardiothoracic surgery associated Acute Kidney Injury: A Single-Center Single-Blind Randomized Controlled Trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs051210154

Enrollment

Registered

2022-01-17

Start date

2022-02-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who are going to be performed open surgical repair for thoracic aortic aneurysm or thoracoa

Interventions

AMIPAREN 200ml, three times a day, three days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients who are going to be performed open surgical repair for thoracic aortic aneurysm or thoracoabdominal aortic aneurysm 2)Patients aged over 20 at the time of consent 3)Patients who are going to admit to ICU after surgery 4)Written informed consent

Exclusion criteria

Exclusion criteria: 1)Hemodialysis patients 2)Preoperative eGFR<15ml/min/1.73m2 3)Patients who are not permitted to admit AMIPAREN 4)Pregnant woman, Nursing mother 5)Emergent surgery 6)Other patients that the research doctor deems inappropriate

Design outcomes

Primary

Measure	Time frame
AKI by postoperative 7 days	—

Secondary

Measure	Time frame
surrogate AKI, eGFR, urine output, RRT, ICU days, hospital days, death	—

Contacts

Public ContactMasahiro Kazawa

National Cerebral and Cardiovascular Center

kazawa.masahiro@ncvc.go.jp+81-6-6170-1070

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026