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Trial of trigger point injections for myofascial pain in patients with cancer

An exploratory, multicenter, open-label, randomized controlled trial of the efficacy and safety of trigger point injections for myofascial pain in patients with advanced cancer

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs051210132
Enrollment
50
Registered
2021-12-16
Start date
2022-01-04
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myofasical pain

Interventions

TPI+ usual care group: For the TPI treatment, 1 mL of 1% lidocaine was injected into each trigger point (maximum 2 sites) using a 26G, 13 mm needle on day 1. Usual care group: For the Usual care, t

Sponsors

Hasuo Hideaki
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Non-curable solid cancers 2) The reference diagnostic criteria of the MRS of Rivers are met 3) Average NRS of pain 24 hours before registration is greater than 4 or 4 4) Hospitalization at the registration within 14 days before registration 5) Age at registration is over 20 years old 6) Sustained main organ function 7) Witten informed consent

Exclusion criteria

Exclusion criteria: 1) There are cancer lesions in the same site as MPS by imaging examination within 4 weeks before registration 2) Change of regular analgesic drugs within 24 hours before registration 3) Psychiatric diseases or conditions that made communication difficult, such as cognitive impairment or disturbance of consciousness 4) Allergy to local anesthetics of the amide type 5) Pregnant and nursing 6) Patient who is considered ineligible for enrolling the study by a principal investigator or sub-investigator

Design outcomes

Primary

MeasureTime frame
Percentage of patients whose average NRS score for the past 24 hours of MPS decreased by 50% or more from before the intervention to 72 hours after the intervention

Secondary

MeasureTime frame
Personalized pain goal achievement, change rate of pain pressure threshold, patient satisfaction, adverse events

Contacts

Public ContactHideaki Hasuo

Kansai Medical University University

hasuohid@hirakata.kmu.ac.jp+81-72-804-0101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026