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Usefulness evaluation of PET probe F18-NKO-035

Evaluation study of usefulness of cancer specific PET probe F18-NKO-035 for lung cancer

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs051200075
Enrollment
12
Registered
2020-10-27
Start date
2020-10-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer LAT1 PET diagnosis

Interventions

Sponsors

Watabe Tadashi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Persons over 20 years old who have been diagnosed with lung cancer with a high probability by pathological diagnosis or CT examination 2) Those who have a solid lesion with a maximum diameter of 2 cm or more in the lung in the CT examination 3) The surgery is planned as above, and pathological evaluation of the lesion can be performed. 4) Persons who have given their written consent to participate in this research

Exclusion criteria

Exclusion criteria: 1) Persons whose general condition is extremely poor 2) Pregnant women and breast-feeding subjects or those who wish to become pregnant 3) Persons who need to use sedatives for PET/CT imaging 4) Persons who are judged to be unsuitable for the research by the investigator

Design outcomes

Primary

MeasureTime frame
Uptake of F18-NKO-035 in lung cancer lesions on PET (Uptake is evaluated using the semi-quantitative evaluation index SUVmax on PET images.)

Secondary

MeasureTime frame
Evaluation of LAT1 expression by immunostaining using surgical specimens of lung cancer lesions Adverse events which occurred after injection of F18-NKO-035 until the end of the examination

Contacts

Public ContactTadashi Watabe

Osaka University Medical Hospital

watabe@tracer.med.osaka-u.ac.jp+81-6-6879-3461

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026