Lung cancer LAT1 PET diagnosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Persons over 20 years old who have been diagnosed with lung cancer with a high probability by pathological diagnosis or CT examination 2) Those who have a solid lesion with a maximum diameter of 2 cm or more in the lung in the CT examination 3) The surgery is planned as above, and pathological evaluation of the lesion can be performed. 4) Persons who have given their written consent to participate in this research
Exclusion criteria
Exclusion criteria: 1) Persons whose general condition is extremely poor 2) Pregnant women and breast-feeding subjects or those who wish to become pregnant 3) Persons who need to use sedatives for PET/CT imaging 4) Persons who are judged to be unsuitable for the research by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Uptake of F18-NKO-035 in lung cancer lesions on PET (Uptake is evaluated using the semi-quantitative evaluation index SUVmax on PET images.) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of LAT1 expression by immunostaining using surgical specimens of lung cancer lesions Adverse events which occurred after injection of F18-NKO-035 until the end of the examination | — |
Contacts
Osaka University Medical Hospital