knee osteoarthritis knee joint medial type
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)Medial knee osteoarthritis and KL classification II or III, 2) over 40 years. 3) consent of patient , 4) outpatient
Exclusion criteria
Exclusion criteria: 1)Severe renal dysfunction or dialysis 2)severe liver dysfunction or liver cirrhosis 3)severe cardiovascular diseases 4)severe cerebrovascular dysfunction 5)severe diabetes mellitus 6)curcumin abuse patients 7)previous knee surgery or intraarticular injection for experimental period or steroid intraarticular injection before 2 months or steroid oral intake before 4 weeks 8)patient who must be excluded by the scientific responsible doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| JKOM, VAS, JOA knee OA score, dependence of NSAIDs | — |
Secondary
| Measure | Time frame |
|---|---|
| Time up and go, knee range of motion biochemical analysis of blood, blood concentration of curcumin | — |
Contacts
National Hospital Organization Kyoto Medical Center