Japanese cedar pollinosis
Conditions
Interventions
Heated K15 Pediococcus acidilactici
Sponsors
Yamamoto Masashi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.individuals aged from 12 to 64 who will give informed consent upon their will 2.individuals who had allergic symptoms such as sneezing, rhinorrhea, nasal obstruction and eye itching during Japanese cedar pollen dispersal season in the past two consecutive years 3.individuals who had shown positive IgE titer more than class II for Japanese cedar pollen in the past three years 4.individuals who can take test material every day and who live or work in Osaka Prefecture
Exclusion criteria
Exclusion criteria: 1.Individuals who show more than class 5 titer of IgE for house dust mite or who show more than class 5 titer of IgE for pets (dogs or cats) and keep corresponding pets at home 2.Individuals who show more titer of IgE for house dust mite that that for Japanese cedar pollen 3.individuals receiving allergen (Japanese cedar pollen) immunotherapy or those who will receive allergen immunotherapy during the study 4.individuals with active diseases,thus,are judged to be inappropriate to join the study by their primary care physicians 5.individuals who are pregnant and brest-feeding and will have a plan of pregnancy during the study 6.individuals who habitually intake prebiotics or probiotics (more than 3 days in a week) 7.individuals who join other clinical studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total nasal symptom-medication score (Severity of allergic symptoms induced by artificial Japanese cedar dispersal evaluated by scoring system) | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of rhinitis, severity of conjunctivitis, medication score, severity of QOL disturbance, objective nasal findings, safety profile, blood test | — |
Contacts
Public ContactKayoko Kawashima
Osaka Habikino Medical Center
Outcome results
None listed