Normal healthy volunteer LAT1 PET diagnosis
Conditions
Interventions
Sponsors
Watabe Tadashi
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) An adult male between 20 and 40 years of age 2) Person who is judged appropriate as a healthy person by a research principal doctor etc. after blood test, urine test and electrocardiogram test 3) Person who have obtained written consent for participation in this study from the applicant
Exclusion criteria
Exclusion criteria: 1) Person with past medical history less than 1 Malignant tumor, endocrine disease, heart failure, severe respiratory disease, liver dysfunction, renal dysfunction 2) Persons who have a history of severe hypersensitivity to components of PET drugs used in this study 3) Persons who have undergone computed tomography (CT), PET or cardiac catheterization within the past year 4) Persons who were judged inappropriate by the investigator as a subject
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimation of whole body dose (effective dose) with F-18 NKO-035 administration (dose is similar to PET examination (4-8 mSv) using nuclide of same half life such as 18F-FDG-PET examination , Confirm that it does not exceed 10mSv.) | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events and side effects Vital signs(systolic/diastolic blood pressure, pulse rate, respiratory rate, temperature) Electrocardiography Clinical examination( hematology, bold biochemistry, urinalysis) | — |
Contacts
Public ContactTadashi Watabe
Osaka University Medical Hospital
Outcome results
None listed