Japanese cedar pollinosis
Conditions
Interventions
K15 Pediococcus acidilactici
Sponsors
Yamamoto Masashi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.individuals aged from 20 to 64 who will give informed consent upon their will 2.individuals who had allergic symptoms such as sneezing, rhinorrhea, nasal obstruction and eye itching during Japanese cedar pollen dispersal season in the past two consecutive years 3.individuals who show positive IgE titer more than class II for Japanese cedar pollen by RAST
Exclusion criteria
Exclusion criteria: 1.individuals receiving allergen (Japanese cedar pollen) immunotherapy or those who will receive allergen immunotherapy during the study 2.individuals with active diseases and judged to be inappropriate to join the study by their primary care physicians 3.individuals who are pregnant and brest-feeding or will have a plan of pregnancy during the study 4.individuals who habitually intake prebiotics or probiotics (more than 3 days in a week) 5.individuals who join other clinical studies 6.individuals who take anti-allergic drugs before or during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total nasal symptom score (Severity of allergic symptoms induced by artificial Japanese cedar dispersal evaluated by scoring system), VAS score of symptomatic severity | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of rhinitis, Severity of conjunctivitis, objective nasal mucosal findings, amounts of nasal discharge | — |
Contacts
Public ContactKayoko Kawashima
Osaka Habikino Medical Center
Outcome results
None listed