Rehabilitation / nutrition intervention trial for elderly patients with esopha geal cancer

Randomized controlled trials of rehabilitation and nutritional intervention during preoperative chemotherapy for esophageal cancer patients over 60 years of age - RENUE study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs051190016

Enrollment

Registered

2019-05-09

Start date

2019-05-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Intervention group 1: Rehabilitation intervention i s performed before or after preoperative chemot herapy is started. Details are as follows. Intervention group 2: Rehabilitation / nutrition int erve

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Histologically confirmed primary esophageal ca ncer. Do not consider organization type. A patien t scheduled for curative esophageal cancer surg ery after the operation of preoperative chemothe rapy.

Exclusion criteria

Exclusion criteria: Cases with milk allergy and intolerance. Cases with active double cancer. In addition, it is judged that registration in this ex am is inappropriate.

Design outcomes

Primary

Measure	Time frame
Muscle mass change rate before and after preoperative chemotherapy	—

Secondary

Measure	Time frame
Adverse events of chemotherapy, nutritional indicators (weight, Alb, lymphocyte count), physical f itness index (grip strength, walking speed), body composition (measured in inbody), perioperative complications, prognosis (no relapse-free survival, Overall survival time), postsurgical swallowing function	—

Contacts

Public ContactSugimura Keijiro

Osaka International Cancer Institute

sugimura-keijiro@kansaih.johas.go.jp+81-6-6945-1181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026