Gastric cancer Gastric cancer
Conditions
Interventions
Patients who assigned to control group does not receive any preoperative intervention.
Preoperative exercise and nutritional prehabilitation are as follows
Exercise: aerobic exercise (1-hour walk) and muscle strengthening training using TheraBand with medium load.
Nutritional support includes recommendation of 2 packs of HMB supplementation
Preoperative exercise and nutritional prehabilitation
Sponsors
Yamamoto Kazuyoshi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Histologically proven primary gastric adenocarcinoma 2. Aged 65 years or older 3. Patients who scheduled to undergo R0 gastrectomy for gastric cancer(open, laparoscopic, robotic) 4. PS 0-2 5. possible to oral intake 6. adequate organ function 7. Written informed consent
Exclusion criteria
Exclusion criteria: 1.Allergy for HMB/Arg/Glu 2.Multiple active cancer with disease-free period less than 5 year, except carcinoma in situ or intra-mucosal disease cured by local therapy. 3.Implementation of pace maker 4.Inappropriate for enrollment judged by physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of change in skeletal muscle mass before surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of patients with sarcopenia after surgery Incidence of postoperative complications Postoperative hospital stay Induction rate of postoperative adjuvant chemotherapy Completion rate of postoperative adjuvant chemotherapy Prognosis Nutritional parameters (weight serum albumin level) | — |
Contacts
Public ContactKazuyoshi Yamamoto
Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute
Outcome results
None listed