Presence of an ileostomy
Conditions
Interventions
During ileostomy closure surgery, after closure of the anterior rectus sheath, the surgical wound will be irradiated with 222-nm ultraviolet light. The irradiation dose will be 500 mJ/cm2 per exposure
Sponsors
Mayu Sakata
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years or older 2. Patients scheduled to undergo ileostomy closure. 3. Patients who have provided written informed consent by personally signing the consent form for this study.
Exclusion criteria
Exclusion criteria: 1. Patients with allergies to dressings, adhesive bandages, or similar products 2. Patients with allergy to povidone-iodine 3. Patients with allergy to triclosan 4. Patients with a history of xeroderma pigmentosum 5. Patients with a history of photosensitivity 6. Patients currently under treatment for abdominal skin diseases 7. Patients with poorly controlled diabetes mellitus, defined as HbA1c of 8.0 % or higher within 90 days prior to enrollment 8. Patients with a history of smoking within 28 days prior to enrollment 9. Patients with a history of wound dehiscence following previous abdominal surgery. 10. Patients in a state of malnutrition, defined as meeting any of the following: a weight loss of 10 % or more within 6 months prior to registration, a BMI less than 18.5 kg/m2 at enrollment, or a preoperative serum albumin level less than 3.0 g/dL. 11. Patients receiving systemic steroids or immunosuppressants (excluding topical or inhaled agents) within 90 days prior to enrollment 12. Patients who are pregnant, breastfeeding, or may be pregnant 13. Patients who have undergone another surgical procedure within 30 days prior to enrollment 14. Patients deemed inappropriate for participation by the principal investigator or sub-investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of anterior rectus sheath dehiscence classified as Clavien-Dindo Grade IIIa or higher within 30 days after surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of superficial surgical site infection (SSI) classified as Clavien-Dindo Grade II or higher Bacterial species identified at the wound site Postoperative length of hospital stay, defined as the period from the day of surgery to the day the physician determines the patient is eligible for discharge. Erythema in the irradiated area Formation of cyclobutane pyrimidine dimers (CPDs) in irradiated tissues Adverse events potentially related to UV irradiation, excluding superficial SSI and erythema in the irradiated area Device malfunctions | — |
Contacts
Public ContactTakagi Toru
Hamamatsu University School of Medicine
Outcome results
None listed