Chronic Lime-Threating Ischemia Chronic Limb Threatening Ischemia, Atherosclerotic obstructive disease, refractory ulcer, foot gangrane
Conditions
Interventions
Washing foot with oxygen nano-bubble instead of conventional water or normal saline
randomised controlled trial
Sponsors
Yamanouchi Dai
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. A patint who consented to this study after adequate explanation 2. A patient whose age is between 20 and 85. 3. A patient suffered from a refractory ulcer for more than 2 weeks 4. A patient whose lesion is graded as 5 in Rutherford Staging
Exclusion criteria
Exclusion criteria: 1. A patient who could not walk at all 2. A patient who could not understand the aim of this study because of dementia or psychotic disease 3. A patient suffered from a severe dermatic disease 4. A patient judged as inappropriate by Principal Investigator or Subinvestigators. 5. A patient who might undergo a major amputation or revascularization for the lower limb
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rate of wound reduction | — |
Secondary
| Measure | Time frame |
|---|---|
| level of white blood cell count, C-reactive protein and procalcitonin in blood tests | — |
Contacts
Public ContactSohei Matsuura
Fujita Health University Hospitsal
Outcome results
None listed