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Vestibular rehabilitation with nGVS for PPPD

Vestibular rehabilitation combined with noisy galvanic vestibular stimulation for persistent postural-perceptual dizziness: a pilot study - PPPD-GVS-1

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs042240022
Enrollment
40
Registered
2024-04-30
Start date
2025-01-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Persistent postural-perceptual dizziness Persistent postural-perceptual dizziness

Interventions

Control group: Vestibular rehabilitation (VR) under the supervision of a physical therapist (PT) once a week for 30 minutes. Home VR for 15 minutes twice daily. For 8 weeks. Treatment group: Control g

Sponsors

Kabaya Kayoko
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Persistent postural-perceptual dizziness 2.Dizziness Handicap Inventory (DHI) >= 36 3.Hospital Anxiety Depression Scale, subscale of anxiety<=10, subscale of depression<= 10 4.Not planning to change to medications that affect dizziness 5.between the ages of 20 and 80 6. Written informed consent

Exclusion criteria

Exclusion criteria: 1. with metal in the body, such as cerebral artery clips or pacemakers 2. orthopedic conditions (especially acute painful conditions such as fractures, sprains, and separated flesh) 3. with heart disease 4. unable to walk independently 5. malignant tumor 6. pregnancy and immediately after delivery 7. sensory disturbance due to severe peripheral circulatory disturbance caused by diabetes mellitus, etc. 8. skin abnormality (infection, wound, etc.) at the electrode application site, or skin allergy to surface electrodes 9. psychiatric symptoms that are considered uncontrollable even with appropriate treatment such as medication 10. other patients who are judged to be inappropriate as subjects

Design outcomes

Primary

MeasureTime frame
Change in DHI scores at pre and 1 months after treatment

Secondary

MeasureTime frame
#total score of DHI #DHI remission rate (14 points or less) and response rate (improvement of 18 points or more) #physical, emotional, functional subscales of DHI #Vertigo Symptom Scale-short form (VSS-sf) #Niigata PPPD Questionnaire (NPQ) #Hospital Anxiety Depression Scale (HADS) #The Patient Global Impression scale (PGI) #Total length of posturography (eye open, eye closed, rubber eye open, rubber eye closed) #TUG Test, Functional Gait Assessment (FGA), Motion Sensitivity Quotient (MSQ) #Visual Analogue Scale about dizziness #Home rehabilitation adherence #adverse events

Contacts

Public ContactKayoko Kabaya

Nagoya City University Hospital

kabaya@med.nagoya-cu.ac.jp+81-52-853-8256

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026