Chronic obstructive pulmonary disease (COPD), In terstitial lung disease (ILD)
Conditions
Interventions
Pulmonary function test and chest X-ray dynamic digital radiography are performed on the subject at visit 1.
The diagnostic imaging workstation Konica Minolta DI-X1 will be used to analyze lung field
dynamic digital chest radiography
Sponsors
Ohkura Noriyuki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet all of the following conditions. 1) Patients who visit the Department of Respiratory Surgery or the Department of Respiratory Medicine at our hospital and are classified by respiratory function tests as 1) COPD patients, 2) ILD patients, 3) patients with mixed ventilation disorder, or 4) patients with normal respiratory function. 2) Age 20 years or older at the time of obtaining written consent. 3) Able to hold a standing position during radiography. 4) Able to take deep breaths and hold breaths according to the respiratory protocol during radiography. 5) Written consent has been obtained from the patient himself/herself after sufficient informed consent for participation in the clinical study.
Exclusion criteria
Exclusion criteria: Patients who meet one or more of the following conditions. 1) The patient is pregnant or may become pregnant. 2) Patients who are judged by the principal investigator or sub-investigator to be unsuitable as research subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint 1: Diagnosis of obstructive ventilatory disorder (FEV1/FVC <0.7) by chest X-ray dynamic digital radiography. Primary endpoint 2: Diagnosis of restrictive ventilatory disorder (predictive vital capacity <80%) by chest X-ray dynamic digital radiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Detection of mixed ventilatory impairment (1 sec/lung volume <0.7 and predicted lung volume <80%) 2) Dynamic parameters (maximum lung field area, tracheal stenosis rate, lung field area change rate) using chest X-ray dynamic analysis of frontal + lateral chest X-ray images 3) Respiratory function (VC, FVC) 4) Dyspnea grade (mMRC grade) 5) Health-related quality of life (CAT score) 6) Lung fields of ventilation analysis images generated from X-ray dynamic images 6) Analysis signal values for the entire lung field and upper, middle and lower lung fields (pulmonary ventilation mapping image) (7) Analyzed signal values for the entire lung fields and the upper, middle, and lower lung fields in the blood flow analysis image generated from the X-ray dynamic image (pulmonary blood flow mapping image) Translated with www.DeepL.com/Translator (free version) | — |
Contacts
Public ContactOhkura Noriyuki
Kanazawa University Hospital
Outcome results
None listed