colorectal adenoma, adenocarcinoma, serrated polyps Colorectal neoplasms, Colorectal polyps
Conditions
Interventions
ESD arm: endoscopic removal by standard ESD using a dedicated knife
Hybrid ESD arm: endoscopic removal by Hybrid ESD using the multi-functional snare (SOUTEN)
Endoscopic mucosal resection, Colonic Neoplasms, Colonoscopy, Adenoma
Endoscopic mucosal resection
Sponsors
Imai Kenichiro
Tanaka Shinji
Yamano Hiro-o
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: i) Patients are at least twenty years old at the time of obtaining consent ii) Patients have non-pedunculated colorectal neoplasms, 20 to 30 mm in size iii) Patients are performance status of zero or one iv) Patients can be followed up for post operative twenty eight days v) Patients provided a written consent based on the patients free will after he or she has a thorough understanding of the instructions given regarding study participation
Exclusion criteria
Exclusion criteria: Patients i) with a history of enrolment in this study, ii) with inflammatory bowel disease or polyposis syndrome, iii) with continuous steroid administration, iv) taking antithronbotic therapy with infeasibility of suspending antithronboticdrugs, v) with blood coagulation disorder, renal failure requring dialysis, or respiratory disease requring oxygen therapy, vi) with pregnancy, vii) with significant mental disorder, viii) with infectious disease requring sistemic therapy, ix) with other invasive colorectal cancer, x) with possible previous treatment, xi) who are determined to be unfit for study by an investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| en bloc R0 resection rate | — |
Secondary
| Measure | Time frame |
|---|---|
| i) Mean procedure time ii) En bloc R0 resection rate adjusted by location and macroscopic type iii) En bloc R0 resection rate in protruded and flat-elevated /sessile lesions iv) En bloc resection rate v) Medical cost for assigned treatment vi) Adverse events including intraprocedural perforation, delayed perforation, delayed bleeding, and post-endoscopic resection coagulation syndrome | — |
Contacts
Public ContactKenichiro Imai
Shizuoka Cancer Center
Outcome results
None listed