Efficacy of liver stiffness measurement by ultrasonography in pediatric liver diseases

Study for the correlation between liver fibrosis evaluated by using abdominal ultrasonography and prognosis in pediatric patients with liver diseases - Study for the correlation between liver fibrosis evaluated by using abdominal ultrasonography and prognosis in pediatric patients with liver diseases

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCTs042190056

Enrollment

210

Registered

2019-07-24

Start date

2019-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric liver disease

Interventions

none

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All pediatric liver disease patients, including healthy controls.

Exclusion criteria

Exclusion criteria: Those who disagreed participating in this study.

Design outcomes

Primary

Measure	Time frame
Relationship between liver and splenic stiffness measured by SWE and autologous liver survival rate in patients with pediatric liver disease.	—

Secondary

Measure	Time frame
Diagnostic capability of SWE for biliary atresia(BA). Diagnosis of existence of esophageal gastric varices from the measured value of SWE at fixed points and the rate of change over time, appearance of new lesions and prediction of bleeding, other portal hypertension, cholangitis, hepato-pulmonary syndrome etc. For liver fibrosis, correlation between measured parameters and liver biopsy results and blood data. Difference in measured values of measured SWE and measured values in the awake state and sedation state.	—

Measure

Time frame

Diagnostic capability of SWE for biliary atresia(BA). Diagnosis of existence of esophageal gastric varices from the measured value of SWE at fixed points and the rate of change over time, appearance of new lesions and prediction of bleeding, other portal hypertension, cholangitis, hepato-pulmonary syndrome etc. For liver fibrosis, correlation between measured parameters and liver biopsy results and blood data. Difference in measured values of measured SWE and measured values in the awake state and sedation state.

—

Contacts

Public ContactYoji Ishizu

Nagoya University school of medicine

y-ishizu@med.nagoya-u.ac.jp+81-52-741-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026