Effect of tDCS on the mitochondrial activity

Effect of transcranial direct current stimulation on the mitochondrial activity in healthy subjects - DoMA

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs042180005

Enrollment

Registered

2018-09-12

Start date

2018-10-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Anodal and cathodal electrodes are placed at the left frontal areas and right frontal areas, respectively. 13-min tDCS with a current intensity of 2 mA is applied twice with a 20-min. After more than

transcranial direct current stimulation

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy right-handed man over twenty years of age With intelligence score IQ>80 on the Japanese Adult Reading Test

Exclusion criteria

Exclusion criteria: People with a history of traumatic brain injury and a episode of an unconsciousness lasting more than 5 minutes People with a history of organic brain diseases People with a history of seizure People with chronic headache People who cannot undergo an MRI scan

Design outcomes

Primary

Measure	Time frame
Analyze changes in binding potential of [18F]BCPP-EF in PET between tDCS and sham stimulation conditions.	—

Secondary

Measure	Time frame
Analyze changes of functional connectivity and cognitive test scores between tDCS and sham stimulation conditions.	—

Countries

Japan, Not applicable

Contacts

Public ContactTomoyasu Bunai

Hamamatsu University School of Medicine

bunai.t@hama-med.ac.jp+81-53-435-2466

Outcome results