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Post-treatment evaluation of malignant brain tumors using 18F-fluciclovine PET/CT

Post-treatment evaluation of malignant brain tumors using 18F-fluciclovine PET/CT: Differentiation of recurrent tumors from radiation necrosis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs041240199
Enrollment
20
Registered
2025-03-07
Start date
2025-04-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignant brain tumor Malignant brain tumor, 18F-fluciclovine, recurrence, radiation necrosis

Interventions

Post-treatment evaluation of malignant brain tumors using 18F-fluciclovine PET/CT
Q000000981
diagnostic imaging

Sponsors

Noguchi Kyo
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Meet all of the following criteria: (1) Diagnosed with malignant brain tumors (malignant glioma or metastatic brain tumor) histopathologically and have been undergoing radiation therapy, suspicion of recurrent tumor or radiion necrosis post-radiation therapy of malignant brain tumors (2) Ages 20 and over (3) We obtain written consent, keep to the rules for participating in the study, undergone the medical examinations and tests set out in the study implementation plan, and are judged by the principal investigator (subinvestigator) to be able to report any symptoms, etc.

Exclusion criteria

Exclusion criteria: Any of the following criteria: (1) Medical history of hypersensitivity to 18F-fluciclovine (2) Principal investigator (subinvestigator) judges to be inappropriate as subjects of this study.

Design outcomes

Primary

MeasureTime frame
18F-fluciclovine uptake Degree uptake of 18F-fluciclovine

Secondary

MeasureTime frame
Consider pitfalls, including the detection of incidental lesions other than the primary evaluation lesions and accumulation in normal tissues.

Contacts

Public ContactNorihito Naruto

Toyama University Hosipital

naruto@med.u-toyama.ac.jp+81-76-434-7326

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026