Patients Requiring Split-Thickness Skin Grafting
Conditions
Interventions
This is a blinded study evaluating the effects of PAL administration on epithelialization, using normal saline administration as the control. Participants are patients scheduled for split-thickness sk
Sponsors
Ebisawa Katsumi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Ages 18 and over 2. Patients undergoing split-thickness skin grafting 3. Subjects who received a sufficient explanation of the purpose and contents of this study voluntarily apply for participation after fully understanding, agreeing in writing
Exclusion criteria
Exclusion criteria: 1. Subjects who cannot keep the affected area rest 2. Subjects with cognitive problems 3. Subjects with decision-making problems 4. Subjects in the department to which the principal investigator and co-investigator belong 5. In addition, subjects judged unsuitable for doctors to carry out this study safely
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference in epithelialization rates between the PAL-treated and saline-treated areas on postoperative day 7. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The difference in epithelialization rates between the PAL-treated area and the saline-treated area on postoperative days 10, 14, 17, and 21 2. The number of days required for complete epithelialization in the PAL-treated area and the saline-treated area 3. Protein analysis of wound exudate (PAL-treated area vs. saline-treated area) | — |
Contacts
Public ContactKatsumi Ebisawa
Nagoya University Hospital
Outcome results
None listed