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Prebiotic Intervention Trial in Atopic Dermatitis

Effects of oligosaccharide (kestose) and dietary fiber (inulin) administration on intestinal microbiota of atopic dermatitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs041240133
Enrollment
30
Registered
2024-11-25
Start date
2025-01-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atopic dermatitis atopic dermatitis

Interventions

Prebiotic group: 3 g of kestose and inulin twice daily, morning and evening. Non-prebiotic group: Observation only.

Sponsors

Sugiura Kazumitsu
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. patients who, after receiving full explanation and with full understanding, give written consent of their own free will to participate in this study 2. patients who are at least 3 years old at the time of consent

Exclusion criteria

Exclusion criteria: Patients deemed inappropriate by the principal investigator or subinvestigator, patients who received antibiotics during the week prior to stool sampling, and patients undergoing stress testing for food allergies.

Design outcomes

Primary

MeasureTime frame
Comparison of intestinal microbiota and intestinal metabolites in patients with atopic dermatitis before and after treatment

Secondary

MeasureTime frame
Skin symptom changes (POEM, ADCT, DLQI, EASI, IGA, BSA, VAS, NRS) Blood tests (IL-10, TRAC, general biochemistry) Evaluation of adverse events (exacerbation of atopic dermatitis, gastrointestinal disorders, and other causally undeniable adverse events)

Contacts

Public ContactTakanaru Aiko

Fujita Health University Hospital

takanaru.aiko@fujita-hu.ac.jp+81-562-93-9256

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026