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Prospective randomized controlled trial for assessing the effect of kestose after pancreaticoduodenectomy

Prospective randomized controlled trial for assessing the effect of kestose after pancreaticoduodenectomy

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs041240047
Enrollment
50
Registered
2024-06-14
Start date
2024-06-14
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The study focuses on diseases targeted for pancreaticoduodenectomy. pancreaticoduodenectomy

Interventions

Oral administration of kestose.
Administration, Oral

Sponsors

Takahara Takeshi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patient who will undergo pancreaticodudodenectomy at Fujita Health University hospital with sufficient understanding of the study and having written informed consent. The patient age is between 20 and 90.

Exclusion criteria

Exclusion criteria: Patients deemed unsuitable for this study by the principal investigator or co-investigators will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
serum albumin level of 24 weeks after the operation

Secondary

MeasureTime frame
The manifestation of fatty liver Changes in glucose tolerance The occupancy rate of beneficial microbiota in the oral and intestinal microbiota The transition of nutritional status and sarcopenia 1 year and 3 years after surgery Dose intensity of postoperative chemotherapy Improvement in nutritional status 6, 12, and 24 weeks after kestose administration as indicated by biological marker scores, including changes in muscle mass evaluated using Inbody, CT, and changes in blood biochemical test values (albumin levels, total lymphocyte count, VitD3, Fe, UIBC, Zn, Mg, ferritin, transferrin, total cholesterol levels, LDL cholesterol levels, HDL cholesterol levels, triglycerides, blood glucose levels, HbA1c, cholinesterase) Prognostic Nutritional Index (PNI)

Contacts

Public ContactYuichiro Uchida

Department of Surgery, Fujita Health University

yuichiro.uchida3389@gmail.com+81-562-93-2869

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026