Healthy participants
Conditions
Interventions
This study is
1) to investigate the standardized uptake value (SUV) of normal organs in healthy adult men (ages 20-30 years) and older adult men (ages 65-80 years), and also 2) to evaluate the effi
Sponsors
Kato Hiroki
Harada Norihiro
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: The following criteria must be met by all participants: 1) Male, in either of two age ranges: 20 to 30 years, or 65 to 80 years 2) Deemed healthy as determined by the physician investigators, based on a physical examination, medical history, vital signs and laboratory tests of blood and urine, and an electrocardiogram 3) Provision of a signed and dated informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Participants who have any of the following criteria will be excluded: 1) Having a malignant tumor, diabetes, or a serious renal, hepatic, cardiac or respiratory disease 2) History of renal, hepatic or cardiac (great arteritis) issues, or any related surgery 3) Receipt of iodinated contrast or MRI contrast agents within the previous month of enrolment 4) Determined by the physician investigators to be clinically unsuitable for the study, based on the screening visit and/or during the study procedures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of age-related standardized uptake value (SUV) of [18F]BCPP-BF in the kidneys, using Positron Emission Tomography/Computed Tomography (PET/CT) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of age-related standardized uptake value (SUV) of [18F]BCPP-BF in the liver and the heart (left ventricular myocardium) Assessment of time-activity curves in major organ tissues (kidney, liver, left ventricular myocardium of the heart, etc.) | — |
Contacts
Public ContactSatomi Ihara
Medical Corporation Kinshukai
Outcome results
None listed