Periodontitis periodontitis
Conditions
Interventions
Experimental group:injecect 0.2mL Nano particle(10mg/mL) solution into periodontal pockets with syringe connected of 27G blunt needle.
Contorol group:injecect 0.2mL distiled saline solution into peri
Sponsors
Fukuda Mitsuo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Healthy adult with periodontal disease as follows Those who have teeth with residual periodontal pocket of 5 mm or more If there are some teeth with a residual periodontal pocket of 5 mm or more, select based on the following criteria 1) Deeper pocket teeth 2) Upper jaw teeth 3) More mesial teeth 4) Right tooth Those who have a stable occlusion (2) Patients aged 20 years or older (3) Patients who can visit the hospital for 2 consecutive weeks (4) Patients who have given written consent to participate in this study
Exclusion criteria
Exclusion criteria: (1) Patients taking antibiotics within the last 3 months (2) Patients who have taken or are taking anti-cancer drugs within 6 months (3) Patients with a history of allergies to Indocyanin Green (4) Patients with a history of allergies to shellfish (5) Pregnant, lactating and potentially pregnant or willing women (6) Patients taking immunosuppressive agents and corticosteroids within the last 3 months (7) Other patients who are judged by the research responsible / shared doctor to be inappropriate as research subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction rate of live bacterial number before and immediately after procedure. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Change rate of red complex before and one week after procedure using real time PCR (2) Change of bleeding on probing before and one week after procedure (3) Comparison of live bacterial cell counts before and 1 week after procedure | — |
Contacts
Public ContactJun-ichiro Hayashi
Aichi Gakuin University Dental Hospital
Outcome results
None listed