Examination of the effect of a test food on weather-related pain and autonomic imbalance

Examination of the inhibitory effect of a test food on the onset of weather-related pain and autonomic imbalance induced by low-pressure exposure

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs041220004

Enrollment

Registered

2022-04-14

Start date

2022-04-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic pain, autonomic imbalance, headache pain

Interventions

After taking the test food, expose the subjects to a low pressure environment. Subjects are assigned to two groups, and each group is subjected to two exposure experiments with a washout period of at

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Meet all of the following selection criteria 1) Those who have consented to participate in the research (adult men and women 20-64 years old) 2) Weather-related pain holders with moderate headaches 3) Those who can participate in one pre-interview and two exposure experiments on the schedule specified by the researcher 4) Those who can submit the results of the medical examination as needed

Exclusion criteria

Exclusion criteria: Those who violate any of the following exclusion criteria 1) Aichi Medical University student 2) Outpatients at Aichi Medical University Hospital Pain Relief Surgery / Pain Center 3) Persons with drug allergies and food allergies 4) Those who plan to take or may take any new treatment during the study period 5) Those who regularly use health foods and supplements such as foods for specified health use and foods with functional claims that are expected to improve pain 6) Pregnant, lactating and wishing to become pregnant during the study period 7) Those who cannot understand the contents of the questionnaire 8) Others (during medication, treatment, etc.) Persons who are judged by the investigator and the person in charge of research to be inappropriate as participants

Design outcomes

Primary

Measure	Time frame
Rate of improvement by test food intake fore changes in NRS score caused by low pressure exposure	—

Secondary

Measure	Time frame
1) Mood score (POMS), anxiety / depression score (HADS) 2) Blood pressure, heart rate, percutaneous arterial oxygen saturation (SpO2), salivary amylase activity 3) Dizziness induction threshold by electrical stimulation of the inner ear 4) Left and right eardrum temperature 5) Artificial weather data	—

Contacts

Public ContactHiroki Sakurai

Aichi Medical University

hsaku@hm.tokoha-u.ac.jp+81-561-62-3311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026