Gastric cancer in elderly patients scheduled for gastrectomy
Conditions
Interventions
Cohort 1
Oral nutritional supplementation (Uplead, 400kcal/100ml) (12 weeks postoperatively)
Cohort 2
Nutrition and exercise program: A combination of oral nutritional supplementation (Uplead), nutri
Sponsors
Bando Etsuro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Histologically proven gastric cancer by endoscopic biopsy. 2) Gastric cancer without distant metastasis or invasion of other organs. 3) Planned curative gastrectomy for gastric cancer. 4) Aged 65 years old or older. 5) Written informed consent.
Exclusion criteria
Exclusion criteria: 1) Planned neoadjuvant chemotherapy for gastric cancer. 2) Need assistance with eating, bathing, dressing, or moving. 3) Severe cardiopulmonary, musculoskeletal, or neurological diseases. 4) Severe mental disease. 5) Allergy for milk or gelatin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cohort 1 Postoperative compliance of Uplead Cohort 2 Participation rate of nutrition and exercise program | — |
Secondary
| Measure | Time frame |
|---|---|
| Cohort 1 1) Safety of Uplead 2) Efficacy of Uplead and dietary intake on postoperative outcomes 3) Patient survey on adverse events and preferences for Uplead Cohort 2 1) Safety of nutrition and exercise program 2) Compliance of nutrition and exercise program 3) Incidence of sarcopenia and frail 4) Physical function 5) Body composition 6) Nutritional status 7) Health related quality of life (HR-QoL) 8) Postoperative complication 9) Compliance of adjuvant chemotherapy 10) Survival outcomes 11) Perioperative compliance of Uplead 12) Efficacy of Uplead on postoperative outcomes 13) Patient survey on adverse events and preferences for Uplead | — |
Contacts
Public ContactKeiichi Fujiya
Shizuoka Cancer Center
Outcome results
None listed