Efficacy of transvaginal antibiotic treatment in preventing recurrence after cystectomy for endometriomas.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs041210114

Enrollment

Registered

2021-12-21

Start date

2022-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian endometrial cyst

Interventions

Administration of trans-vaginal antibiotics

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Patients after cystectomy for endometriomas 2. Patients who are not applicable for pseudo-menopausal therapy with hormonal treatment after cystectomy 3. Patients whose endometrium are positive for bacteria that are causative agents of ovarian endometriotic cysts 4. Written informed consent

Exclusion criteria

Exclusion criteria: 1.Patients with hypersensitivity to metronidazole 2.Patients who continue to use GnRHa, LEP or OC as hormonal therapy for the treatment of endometriosis after surgery 3. Patients whom the doctor considers unsuitable

Design outcomes

Primary

Measure	Time frame
Recurrence rate of ovarian endometriotic cysts	—

Secondary

Measure	Time frame
Time to recurrence of endometriosis, Rate of adverse events, Menstrual pain and non-menstrual pain ratings (general patient assessment (VAS), general physician assessment (VAS))	—

Contacts

Public ContactSatoko Osuka

Nagoya University Hospital

satokoosuka@med.nagoya-u.ac.jp+81-52-744-2261

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026