Oligospermia, asthenozoospermia, malformation spermia, azoospermia, SDF rate 16% or more
Conditions
Interventions
Measure the SDF rate of raw semen before and after ingestion of the supplement "Pregna (for women)" for patients with poor semen findings, and examine whether the SDF rate improves (decreases) by inge
Sponsors
Takayama Erina
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Target disease name and diagnostic method Those who have been diagnosed with oligospermia (less than 75 million animals / mL), asthenozoospermia (less than 50%), azoospermia (95% or more), azoospermia (less than 2.0 mL) or SDF rate of 16% or more. 2) Age 20-60 years old 3) Gender male 4) Threshold based on clinical test values, etc. SDF rate of raw semen is 16% or more 5) Written patient consent Person with written consent from the person
Exclusion criteria
Exclusion criteria: 1) Patients taking supplements or drugs that have the same effect as antioxidant compounds 2) Patients wtih severe oligospermia, spermatogenesis disorders (hypothalamus / pituitary disorders, varicocele, cryptorchidism, azoospermia, chromosomal abnormalities (Klinefelter syndrome), etc.), obstructive azoospermia , retrograde disorder, and accessory genital dysfunction 3) Patients with diarrhea, vomiting or allergies (containing soybeans) as therapeutic agents 4) Patients with serious liver disease (AST (GOT) or ALT (GPT) of 100 IU / L or more) 5) Patients who participated in other clinical trials (clinical trials) that lead to improvement of semen findings within 3 months before the start of study drug administration 6) Patients who are judged by the principal investigator or the investigator to be inappropriate as research subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SDF rate 3 months after administration | — |
Secondary
| Measure | Time frame |
|---|---|
| SDF change amount, SDF change rate, semen findings (liquid volume, total sperm concentration, motility, malformation rate, motility) Amount of change = 3 months after administration-before administration, rate of change = (3 months after administration-before administration) / before administration | — |
Contacts
Public ContactHiroki Takeuchi
Department ofObstetrics and Gynecology, Graduate School of Medicine
Outcome results
None listed