Periodontal patients with residual pockets at SPT stage Periodontitis
Conditions
Interventions
Experimental group: inject 0.2ml Mano particle(10mg/ml) solution into periodontal pockets with syringe connected of 30G blunt needle.
Contorol group: inject 0.2ml sterile distilled water into periodo
Sponsors
Fukuda Mitsuo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Healthy adults with periodontal disease as follows, 1) who have single-root teeth with over 5mm residual pockets depth. 2) who have stable occulusion. (2) Patients aged from 20 to 85 years old at registration. (3) Patients who have written informed content to participate in this study for 2 consecutive weeks.
Exclusion criteria
Exclusion criteria: (1) Patients who have taken antibiotics within the last 3 months. (2) Patients with diabetes. (3) Patients who have taken or taking anticancer drugs within 6 months. (4) Patients with a history of allergy to indocyanine green. (5) Patients with a history of allergy to crustaceans. (6) Women who are pregnant, breastfeeding or may or may be pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of live bacteria number immediately after procedure. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Reduction of live bacteria number one week after procedure (2) Change of bacterial flora one week after procedure (3) Change of peiodontal pocket depth after procedure | — |
Contacts
Public ContactJun-ichiro Hayashi
Aichi Gakuin University Dental Hospital
Outcome results
None listed